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Day 12

A collection of 3 issues

65 COAGULATION & ANTICOAGULANTS

# 66 COAGULATION & ANTICOAGULANTS Detailed notes Haemostasis is the body's response to vessel injury. It must be fast enough to stop blood loss, but tightly regulated to avoid pathological thrombosis. The MRCS Part A consistently tests three things here: the cascade, the drugs that target it, and the

42 AORTIC DISEASE

# Aortic Disease The aorta carries the entire cardiac output, so when it dilates, dissects or ruptures the consequences are catastrophic. Aortic disease is high-yield in MRCS Part A because the same anatomical landmarks, embryological origins and pathological mechanisms reappear across vascular, anatomy and pathology SBAs. 👩‍⚕️ Anchor concept: AAA = loss

77 BLOOD PRODUCTS

# 78 BLOOD PRODUCTS Transfusion questions in MRCS Part A cluster around three themes: blood group compatibility, which component to give for which problem, and recognising the transfusion reactions. 👩‍⚕️ Three anchors: FFP lasts 24 h once thawed (1 year frozen); UK transfusion recipients can NEVER donate (vCJD); citrate in stored blood